Annales françaises d’anesthésie et de réanimation – Vol. 21 – N° 4 – p. – Alcalose métabolique sévère et buveur de bière – EM|consulte. L’alcalose métabolique pure ou mixte est fréquente en réanimation, notamment chez les patients BPCO au cours du sevrage de la ventilation. Download Citation on ResearchGate | Alcalose métabolique sévère avec hypokaliémie révélant un syndrome de Cushing paranéoplasique | Metabolic alkalosis.

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Metabolic alkalosis is a metabolic condition in which the pH of tissue is elevated beyond the normal range 7.

Metabolic alkalosis

This is the result of decreased hydrogen ion concentration, leading to increased bicarbonateor alternatively a direct alcalise of increased bicarbonate concentrations. The condition typically cannot last long if the kidneys are functioning properly.

Mild cases of metabolic alkalosis often causes no symptoms. Typical manifestations of moderate to severe metabolic alkalosis include abnormal sensationsneuromuscular irritability, tetanyabnormal heart rhythms usually due to accompanying electrolyte abnormalities such as low levels of potassium in the bloodcomaseizuresand temporary waxing and waning confusion.


The causes of metabolic alkalosis can be divided into two categories, depending upon urine chloride levels.

Metabolic alkalosis treated with intravenous hydrochloric acid.

Blood product administration since this contains sodium citrate which is then metabolized into sodium bicarbonate. Typically, this is seen with large volume transfusions such as more than 8 units.

Decreases in albumin and phosphate will cause metabolic alkalosis. Compensation for metabolic alkalosis occurs mainly in the lungs, which retain carbon dioxide CO 2 through slower breathing, or hypoventilation respiratory compensation.

Metabolic alkalosis treated with intravenous hydrochloric acid.

CO 2 is then consumed toward the formation of the carbonic acid intermediate, thus decreasing pH. Respiratory compensation, though, is incomplete.

But, because respiration slows, there’s an increase in pCO 2 which would cause an offset of the depression because of the action of the central chemoreceptors which are sensitive to the partial pressure of CO 2 [ citation needed ] in the cerebral spinal fluid. So, because of the central chemoreceptors, respiration rate would be increased.

To calculate the expected pCO2 in the setting of metabolic alkalosis, the following equations are used:. To effectively treat metabolic alkalosis, the underlying cause s must be corrected. A trial of intravenous chloride-rich fluid is warranted if there is a high index of suspicion for chloride-responsive metabolic alkalosis caused by loss of gastrointestinal fluid e. From Wikipedia, the free encyclopedia. Metabolic alkalosis Davenport diagram Specialty Endocrinology Metabolic alkalosis is a metabolic condition in which the pH of tissue is elevated beyond the normal range 7.


Cardiac Disease and Critical Care Medicine”. Arterial Blood Gases Made Easy. Churchill Livingstone 1 edition 18 Sep Journal of Ultrasound in Medicine. Journal of the American Alcaoose of Nephrology: Electrolyte imbalance and acid—base imbalance E86—E87 Metabolic Contraction alkalosis Respiratory.

Mixed disorder of acid-base balance. Retrieved from ” https: Infobox medical condition new All articles with unsourced statements Articles with unsourced statements from November Views Read Edit View history. This page was last edited on 1 Octoberat By using this site, you agree to the Terms of Use and Privacy Policy.

Qlcalose ICD –