There are two widely used definitions of exacerbation. The Anthonisen definition is based on the presence of one or more of three cardinal symptoms, including. La enfermedad pulmonar obstructiva crónica (EPOC) es una entidad que causa una gran 9. eisner md, Anthonisen n, coultas d, et al. 38 | Proceso asistencial integrado del paciente con EPOC exacerbado. Anthonisen NR, Manfreda J, Warren CP, Hershfield ES, Harding GK, Nelson NA.
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Sleep quality is lower in patients with chronic obstructive pulmonary disease COPD than in healthy individuals. Although episodes of nocturnal saturation can reasonably be supposed to increase morbidity and mortality in these patients, the diagnostic importance of these desaturations has not been demonstrated.
However, desaturation episodes must be detected in patients with COPD and sleep apnea-hypopnea syndrome SAHSsince morbidity and mortality are higher when these two entities are combined than when they occur separately. Further studies are required to elucidate the role of physiopathological alterations during sleep, the importance of nocturnal desaturations and the role of oxygen therapy and ventilatory support, as well as the utility of some drugs that could improve sleep quality and gas exchange in these patients.
Chronic obstructive pulmonary disease and sleep apneas. However, desaturation episodes must be detected in patients with COPD anthonien sleep apnea-hypopnea epo SAHSsince morbidity and mortality are higher when these two entities are combined than when they occur separately.
Further studies are required to elucidate the role of physiopathological alterations during sleep, the importance of nocturnal desaturations and the role of oxygen therapy and ventilatory support, as well as the utility of some drugs that could improve sleep quality and gas exchange in these patients. Lancet,pp.
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